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Based on AUCoverall pharmacological activity of cilostazol increases 19when co-administered with diltiazemBased on these datano dose adjustment is necessary.

The effect of CYP3A4 and CYP2C19 inducerssuch as carbamazepinephenytoinrifampicin and StJohn’s worton cilostazol pharmacokinetics has not been evaluatedThe antiplatelet effect may theoretically be altered and should be carefully monitored when cilostazol is co-administered with CYP3A4 and CYP2C19 inducers.

Pletal is a prescription medicine used to reduce the symptoms of intermittent claudication and can increase your ability to walk further distances.

Use this medication regularly to get the most benefit from itRemember to use it at the same times each day.

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