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Patients should tell their doctor and pharmacist if they are allergic to coumadine or flagyl, or any other medications, or any of the ingredients in their product forms.

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COUMADIN for injection vials yield 5 mg of warfarin after reconstitution with 2.7 mL of Sterile Water for Injectionmaximum yield is 2.5 mL of a 2 mg/mL solutionNet content of vial is 5.4 mg lyophilized powder.

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222An overdose can cause excessive bleeding.

Select the initial dose based on the expected maintenance dosetaking into account the above factorsModify this dose based on consideration of patient-specific clinical factorsConsider lower initial and maintenance doses for elderly and/or debilitated patients and in Asian patientssee Use in Specific Populations8.5and Clinical Pharmacology12.3Routine use of loading doses is not recommended as this practice may increase hemorrhagic and other complications and does not offer more rapid protection against clot formation.

All medicationsincluding warfarinshould always be kept out of the reach of children and pets.

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