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All patients on long-term therapy with this preparation should be questioned and examined periodicallyincluding the testing of knee and ankle reflexesto detect any evidence of muscular weaknessIf weakness occursdiscontinue the drug.

Other medical conditionsIf you have stomachnervebloodor skin disorderstalk to your doctor about how this medication may affect your medical conditionhow your medical condition may affect the dosing and effectiveness of this medicationand whether any special monitoring is needed.

Children are especially sensitive to the 4-aminoquinoline compoundsA number of fatalities have been reported following the accidental ingestion of chloroquinesometimes in relatively small doses0.75 g or 1 g in one 3-year-old childPatients should be strongly warned to keep these drugs out of the reach of children.

Liver diseaseIf you have liver diseaseyou may need a lower dose of this medicationTalk to your doctor about how this medication may affect your medical conditionhow the medical condition may affect the dosing and effectiveness of this medicationand whether any special monitoring is needed.

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